Place the sense resistor (RSNS) close to the TPS4810x-Q1 and then connect RSNS using the Kelvin techniques. Refer to Choosing the Right Sense Resistor Layout for more information on the Kelvin techniques.
Choose a 0.1µF or higher value ceramic decoupling
capacitor between VS terminal and GND for all the applications. Consider adding RC network
at the supply pin (VS) of the controller to improve decoupling against the power line
disturbances.
Make the high-current path from the board input to the load, and the return path, parallel and close to each other to minimize loop inductance.
Place the external MOSFETs close to the controller GATE drive pins (G1PU/PD and G2) such that the GATE of the MOSFETs are close to the controller GATE drive pins and forms a shorter GATE loop. Consider adding a place holder for a resistor in series with the Gate of each external MOSFET to damp high frequency oscillations if need arises.
Place a TVS diode at the input to clamp the voltage transients during hot-plug and fast turn-off events.
Place the external boot-strap capacitor close to BST and SRC pins to form very short loop.
Connect the ground connections for the various components around the TPS4810x-Q1 directly to each other, and to the TPS4810x-Q1 GND, and then connected to the system ground at one point. Do not connect the various component grounds to each other through the high current ground line.